CBD oil is well-known for relieving pain and anxiety without the risk of dependency. But not all CBD oil is the same. We’ve done the research, looked at lab results, and talked to the experts to bring you this list of the best CBD oil for pain and anxiety relief.
Chronic pain and anxiety are two of the most common causes of distress in the country. In fact, nearly one in five Americans suffers from anxiety, and the figures for chronic pain are strikingly similar. If you’re one of the many people dealing with one of these conditions on a daily basis, you’re not alone. But, you do need to be careful when seeking treatment.

Prescription drug abuse has skyrocketed in recent years, and nearly all of these drugs were originally prescribed for pain or anxiety. We’re not saying that these drugs are bad, but if you’re not careful, short-term relief can quickly turn into a long-term nightmare. This has led many to seek out natural forms of relief that don’t have a risk of dependency. One of the options that has been growing in popularity is CBD oil.
Studies have suggested that CBD oil can be very effective at reducing pain and anxiety while improving quality of life. As a completely natural, plant-based and non-dependency forming compound, CBD has the potential to bring relief to millions around the world with virtually no side-effects.
While the FDA has only approved one drug that contains CBD, the medical world is abuzz with success stories and promising results related to CBD oil. In this article, we’ll tell you exactly which products have shown to offer the best pain and anxiety relief, and we’ll tell you how to get your hands on them today.
What is CBD Oil?
CBD oil is a natural supplement that can be mixed with your food or drink or taken sublingually (under the tongue). It affects the body in a number of beneficial ways. For example, it has been shown to alleviate pain, reduce the occurrence of seizures, relieve anxiety and depression, regulate appetite and sleep, curb nausea and more.
CBD oil is made by extracting a compound called cannabidiol (CBD) from the cannabis plant and then infusing it into a carrier oil such as hemp seed oil or coconut oil.
CBD oil is non-psychoactive, meaning it can’t “get you high.” Most CBD oil is made from hemp, not marijuana. Hemp contains very little THC (the psychoactive ingredient that gets you high or stoned). In most cases, nearly all (or all) of the remaining THC is removed during the extraction process.
Some CBD oil contains only one cannabinoid (a compound extracted from cannabis), namely, CBD. This is called “CBD isolate.” Though most CBD oil contains a range of beneficial cannabinoids and essential oils. This is known as “full-spectrum” CBD oil.
Full-spectrum CBD oil is more popular because studies have shown that it delivers more benefits to the user. It should be mentioned, however, that full-spectrum blends may contain trace amounts of THC. While this will go unnoticed by most, it may act as a trigger for those with more severe anxiety. Also, even trace amounts of THC can show up on a drug test.
How Does CBD Relieve Pain and Anxiety?
Studies are still being conducted to understand all of the ways the CBD helps to relieve pain and anxiety, but so far, scientists have observed CBD interacting with the body at a molecular level in over 65 different ways. Let’s take a look at a few of them that directly relate to pain and anxiety relief.
This is all pretty complicated, we know, but the important thing to remember is that the effect CBD has on the body is completely natural. In fact, the human body has a system in place that is responsible for the production and reception of cannabinoids. This is called the endocannabinoid system, and it’s just as vital to your health as your circulatory system, nervous system, or any other of system.
The endocannabinoid system helps your body to regulate a number of functions such as appetite, sleep, stress and more. Taking CBD oil simply provides your body with more of the natural compounds that it needs to do its job. The result is a clearer mind, lower levels of inflammation, a reduction in pain, anxiety, and depression, better sleep and much more.
Top CBD Brands for Pain and Anxiety Relief
There’s a lot of work that goes into producing CBD oil, and not every company is up to the task. In the past, there were only a few CBD oil producers, but now that CBD is growing in popularity, new producers and vendors are popping up every day. This can make it difficult to know which brands to trust.
We got to the bottom of all of these questions and many more during our research on the best CBD oil for pain and anxiety relief. At the end of the day, we found six brands that we would strongly recommend. From the growth of the hemp plant to the extraction process to the packaging, the following companies are dedicated to delivering CBD oil that is pure and extremely effective.
Charlotte’s Web CBD
Charlotte’s Web is one of the most exciting new CBD oil brands on the market. They take dedication to purity and consistency to new levels.
To start, Charlotte’s Web tests the water that they use to nourish their Hemp plants. From there, the seedlings are tended and tested daily (by hand) until the plants reach CW’s high standards. The result is a CBD oil that is incredibly pure and consistent.
Charlotte’s Web CBD Oil is its main product and the primary focus of the brand. It was developed specifically to help those with physical problems, so you can expect exceptional relief from pain. It comes in four different strength options, including one that is stronger than even the highest strength options of competitors.
CW CBD oil is already quite potent, making their strongest option one of the best for more severe pain and anxiety.
Charlotte’s Web CBD oil is made from organic, hand-tended, non-GMO hemp grown in the USA.
Green Roads
Green Roads has an incredible story to tell. The founder of this brand suffered an injury previously, and as a result of the pain medication he was prescribed, he sunk into a cycle of addiction that ruined years of his life. After his recovery, he created Green Roads as a way to help others choose CBD as a natural and non-addictive way to deal with pain.
Green roads CBD oil was formulated with the assistance of pharmacists to provide the real relief from pain and anxiety even at small doses. The highly scientific process and extensive testing employed by Green Roads results in CBD oil with a very high concentration of cannabinoids. And, with seven strength options to choose from, it’s very easy to find the right dose.
Green Roads CBD oil is made from organic, non-GMO hemp.
The CBDistillery
The CBDistillery was founded by Colorado natives who believe that high-quality CBD should be available to all. For this reason, they offer some of the best-priced CBD oil that we’ve come across. The CBDistillery’s production process may not be quite as rigorous as some of the others on this list, but the oil they offer is still highly effective and 100% natural.
What we love the most is the variety of oils and strength options available. The CBDistillery makes full-spectrum and CBD-only blends that start out at 250mg and climb to an incredible 5000mg of CBD per bottle. With concentrations like that, The CBDistillery is one of the only companies offering seriously strong levels of CBD that can counter high levels of pain and anxiety. Even at extremely high levels of CBD, this company maintains prices as low as half that of many other brands.
The CBDistillery CBD oil is made from non-GMO hemp grown using organic practices.
NuLeaf Naturals
NuLeaf Naturals is the only brand on this list that produces CBD oil exclusively. They only have one product, but according to many users, it’s the best CBD oil on the market.
What makes NuLeaf special is their dedication to perfection. They grow their own hemp, which they augment using advanced cloning techniques, and each plant undergoes subcritical and supercritical extraction without the use of heat. This creates an oil that has lost absolutely none of the vital cannabinoids found in the hemp plant.
This ultra-rich CBD oil is one of the highest rated for anxiety and pain relief despite it being available only at one level of strength. While this may turn off some who need higher concentrations of CBD for pain and anxiety relief, we’d recommend trying to up the dosage of NuLeaf before jumping ship.
NuLeaf Naturals CBD oil is made from organic, non-GMO hemp grown in Colorado.
Koi CBD
Koi CBD is a California-based company that produces a range of CBD products. Their CBD oil is some of the highest rated due to its purity and accessibility. It’s difficult for many to start taking CBD oil due to its taste, but Koi has some of the best tasting flavored CBD oils available. Despite the addition of flavors, each oil still tests at a purity level of over 99%.
One thing that sets Koi CBD apart is that they make sure all of their products contain 0% THC—even the full-spectrum CBD products. This is great news for those who suffer from anxiety and can’t consume even trace amounts of THC.
Higher concentrations of Koi CBD oil are effective at relieving pain and are known to produce a relaxing sensation in users.
Koi CBD oil is made from organic hemp grown in Colorado
Things to Keep in Mind
CBD oil is an all-natural supplement that has helped thousands find relief from chronic pain and anxiety. CBD oil has virtually no side effects, no risk of dependency, and it’s inexpensive and easily accessible. Because of this, it may seem as if there’s no reason not to try it. While we are CBD aficionados and personally recommend that everyone take CBD oil for its multitude of benefits, there are some things that you should keep in mind.